METHOD FOR PRODUCTION OF BLOCK-COPOLYMER-DRUG COMPOSITE

摘要

FIELD: pharmaceuticals. ^ SUBSTANCE: claimed method includes step of dissolution of AB-type block-copolymer, comprising hydrophilic polymer structure unit representing polyethylene oxide derivatives and hydrophobic polyamino acid structure fragment representing polyasparaginic acid together with drug (doxorubicine or salt thereof) in mixed solvent containing water and low boiled water miscible organic solvent followed by concentration of obtained solution. ^ EFFECT: new block-copolymer-drug composite. ^ 4 cl, 2 tbl, 3 ex