发明名称 |
Imidazolinoxyl derivatives |
摘要 |
This invention offers the compounds which exhibit a coronary blood vessel dilating action which is long-acting. (Constitution) Novel imidazolinoxyl derivatives represented by a general formula (1). A compound A in which R is COOH is given in an example. <IMAGE> (1) (Merit) The compounds of the present invention can be directly administered, after diluting to a suitable concentration with a phosphate buffer or the like, to blood vessel which is required to be relaxed and dilated whereby a significant and long-acting relaxing action is resulted though, in a blood flow, they are quickly inactivated and excreted and no side effect is noted.
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申请公布号 |
US5536744(A) |
申请公布日期 |
1996.07.16 |
申请号 |
US19940363614 |
申请日期 |
1994.12.23 |
申请人 |
DOJINDO LABORATORIES |
发明人 |
OKUMURA, KEN;TSUNODA, RYUSUKE;MAEDA, HIROSHI;AKAIKE, TAKAAKI;SATO, KEIZO;SASAMOTO, KAZUMI;KATAYAMA, YOSHIKI |
分类号 |
C07D233/52;A61K31/415;A61K31/70;A61K31/7028;A61P9/08;A61P9/10;C07D233/20;C07D233/22;C07D233/24;C07D233/26;C07D405/12;C07H15/26;(IPC1-7):A61K31/415 |
主分类号 |
C07D233/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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