发明名称 COMPUESTOS DERIVADOS DE AMIDAS SUSTITUIDAS; PROCESO PARA LA PREPARACION DE DICHOS COMPUESTOS; COMPOSICION FARMACEUTICA QUE COMPRENDE A DICHOS COMPUESTOS; Y SU USO PARA EL TRATAMIENTO DEL INSOMNIO, DISFUNCION SEXUAL, ESQUIZOFRENIA, ENTRE OTRAS ENFERME
摘要 <p>The present invention relates to compounds of formula I wherein Ar1, Ar2, Ar3, n, and R1 to R8 are as defined herein and to pharmaceutically suitable acid addition salts, optically pure enantiomers, racemates or diastereomeric mixtures thereof. These compounds are orexin receptor antagonists and may be useful in the treatment of disorders, in which orexin pathways are involved, like sleep disorders.</p>
申请公布号 CL2008000641(A1) 申请公布日期 2008.09.12
申请号 CL20080000641 申请日期 2008.03.04
申请人 F. HOFFMANN-LA ROCHE AG. 发明人 LUCA GOBBI, HENNER KNUST, PARICHERHR MALHERBE, MATTHIAS NETTEKOVEN, EMMANUEL PINARD, OLIVIER ROCHE Y MARK ROGERS-EVANS.
分类号 A61K31/343;A61P15/00;A61P25/18;A61P25/20;C07D307/87 主分类号 A61K31/343
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