| 发明名称 |
BORONIC ACID AND ESTER INHIBITORS OF THROMBIN |
| 摘要 |
Novel boronic acid and ester and carboxyl-modified amino acid compounds of formula (I): R1-Z-CHR1-A, which are inhibitors of trypsin-like enzymes, are disclosed, where R1, Z, R2 and A are defined within.
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| 申请公布号 |
CA2208971(A1) |
申请公布日期 |
1996.07.11 |
| 申请号 |
CA19952208971 |
申请日期 |
1995.12.13 |
| 申请人 |
THE DU PONT MERCK PHARMACEUTICAL COMPANY |
发明人 |
DUNCIA, JOHN JONAS VYTAUTAS;WEBER, PATRICIA CAROL;AMPARO, EUGENE CRUZ;WITYAK, JOHN;MILLER, WILLIAM HENRY;SANTELLA, JOSEPH BASIL III;PACOFSKY, GREGORY JAMES |
| 分类号 |
C07D249/08;C07F5/02;(IPC1-7):C07F5/02;C07F7/10;C07F9/38;A61K31/69;A61K31/695 |
主分类号 |
C07D249/08 |
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