| 摘要 |
A rotor (2a-2e) for collecting and centrifuging biological fluids in a range of volumes. The rotor includes an elastic impermeable diaphragm (31) which defines at least a portion of a variable-volume processing chamber (30), where the fluid is centrifuged. The rotor includes a rigid mounting member (28), to which the diaphragm is mounted and which is held and spun by a chuck. Preferably, this rigid mounting member includes a boundary wall (10) which together with the elastic diaphragm defines the chamber. The boundary wall may be a substantially imperforate circular wall which extends to the periphery of the processing chamber but defining one opening, preferably near the axis of rotation, permitting a conduit (13) or conduits (83, 93, 163, 165, 188) to pass therethrough so as to be in fluid communication with the processing chamber. The rotor may include a separate structure (40, 190, 244) for controlling the flow of liquid out of the chamber into the conduit. In a preferred embodiment, this outlet-control structure is a perforate, substantially rigid wall or plate (40), located within the processing chamber and mounted adjacent the rigid boundary wall. In an alternative embodiment, the outlet-control structure for controlling flow from the processing chamber to the conduit may include at least one tube or preferably a set of tubes (190), wherein each tube provides fluid communication between the chamber and the conduit. In one preferred embodiment, grooves (244) in the boundary wall may be used as the outlet-control structure. 00000 |
