摘要 |
<p>The invention describes a rapid single step assay suitable for the detection or quantification of B-lactam antibiotics and B-lactamases. The assay can be performed directly on samples of food, such as milk and meat, blood or serum and is useful in determining the suitability of a particular antibiotic in treating a particular bacterial infection and in diagnosis of a bacterial infection. The assay is useful in determining and quantifying B-lactam antibiotic resistance. The figure illustrates B-lactamase-catalyzed hydrolysis of benzylpenicillin. The assay can be performed on an IGEN Origen Analyzer.</p> |