摘要 |
A pyridylalkyl phenyl sulfone derivative which has thromboxane A2 and prostaglandin H2 antagonisms and the effect of inhibiting the synthesis of thromboxane A2, is useful as an antithrombotic agent and an antiallergic agent, and is represented by general formula (1), wherein X represents hydrogen, halogeno, lower alkyl, lower alkoxy, hydroxy, nitro, cyano or trifluoromethyl; R represents -O-(CH2)a-CO2-R1, -(CH2)a-CO2-R1, -CR2=CR3-CO2-R1 or -CR2R3-CR4R5-CO2-R1 (wherein R1, R2, R3, R4, and R5 represent each hydrogen or lower alkyl; and a represents an integer of 0 to 5); and 1, m and n represent each an integer of 0 to 5. |