| 发明名称 |
MURINE MONOCLONAL ANTI-IDIOTYPE ANTIBODY 3H1 |
| 摘要 |
The present invention provides a monoclonal anti-idiotype antibody 3H1 that escapes immune tolerance and elicits a specific immune response to CEA in mice, rabbits, monkeys, and patients with advanced CEA-associated disease. This invention also provides compositions which can be used in the detection or treatment of CEA-associated tumors mimics a specific epitope on carcinoembryonic antigen and a hybridoma that produces 3H1.
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| 申请公布号 |
CA2209172(A1) |
申请公布日期 |
1996.07.04 |
| 申请号 |
CA19952209172 |
申请日期 |
1995.12.28 |
| 申请人 |
UNIVERSITY OF KENTUCKY |
发明人 |
KOHLER, HEINZ;FOON, KENNETH A.;CHATTERJEE, SUNIL K.;CHATTERJEE, MALAYA |
| 分类号 |
G01N33/53;A61K38/00;A61K39/00;A61K39/12;A61K39/39;A61K39/395;A61K48/00;A61P35/00;A61P37/04;C07K14/535;C07K14/55;C07K16/42;C07K19/00;C12N5/10;C12N15/02;C12N15/09;C12P21/02;C12P21/08;C12R1/19;C12R1/91;G01N33/574;G01N33/577;(IPC1-7):C12N5/18 |
主分类号 |
G01N33/53 |
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