发明名称 |
6-[TRIAZOLYL[3-(TRIFLUOROMETHYL)PHENYL¦METHYL¦-2-QUINOLINONES AND -QUINOLINETHIONES |
摘要 |
This invention is concerned with the compounds of formula (I), the pharmaceutically acceptable acid addition salts and the stereochemically isomeric forms thereof, wherein R1 is hydrogen, amino or C1-4alkyl; R2 is hydrogen, halo or C1-4alkyl; R3 is hydrogen, halo or C1-4alkyl; Y is O or S, and -X1 = X2- is a bivalent radical having the formula: -N = CH- (a-1) or -CH = N- (a-2); compositions containing the same, and processes of preparing these compounds. It further relates to their use as a medicine, in particular their use as a medicine to treat keratinization disorders.
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申请公布号 |
CA2207268(A1) |
申请公布日期 |
1996.07.04 |
申请号 |
CA19952207268 |
申请日期 |
1995.12.21 |
申请人 |
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP |
发明人 |
VENET, MARC GASTON;MABIRE, DOMINIQUE JEAN-PIERRE;SANZ, GERARD CHARLES |
分类号 |
C07D401/06;A61K8/14;A61K8/49;A61K31/47;A61P17/00;A61P43/00;C07D521/00;(IPC1-7):C07D401/06 |
主分类号 |
C07D401/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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