| 摘要 |
<p>Compounds of formula (A), wherein X is oxy, thio, -S(O)- or -S(O)2-; Y is carbonyl or methylene; R1, R2, R3 and R4 are hydrogen or substituents; R4 is alkyl or cycloalkylmethyl; and Z is an acidic residue; are useful as squalene synthetase inhibitors in the treatment of hypercholesterolemia, atherosclerosis, fungal or Alzheimer's diseases.</p> |
