| 摘要 |
Amidinonaphthyl furancarboxylate derivatives of the formula I <IMAGE> I <IMAGE> wherein A is a single bond or A denotes (a) a phenyl group, cyclopentyl group, or cyclohexyl group, (b) an alkenylphenyl group, alkylphenyl group, phenylalkenyl group, or phenylalkyl group wherein alkyl is C1 to C7 alkyl and alkenyl is C2 to C7 alkenyl, (c) a C1 to C18 alkyl or C2 to C7 alkenyl group which may be substituted by one or two substituents selected from C1 to C5 alkyl groups and quanidino groups, wherein an alkyl substituent together with the carbon atom to which it is attached may form a cycloalkyl ring having from 3 to 6 carbon atoms, or said C1 to C5 alkyl may itself be substituted by a C3 to C6 cycloalkyl ring, or (d) -(CH2)n-NH-CO-(CH2)n' wherein n and n' may be the same or different and represent an integer from 1 to 4; and wherein R denotes (e) a hydroxyl group, (f) a C1 to C7 alkoxy group which may be mono- or disubstituted by C1 to C5 alkyl, (g) a phenyl-C1-C4alkoxy group, (h) -OAl(OH)2, (i) an amino group, (j) <IMAGE> or (k) <IMAGE> and pharmaceutically acceptable acid addition salts thereof, useful as pharmaceuticals.
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