发明名称 Condensed thiophene compound and pharmaceutical use thereof
摘要 A condensed thiophene compound represented by general formula: <IMAGE> (I) or a pharmaceutically acceptable salt thereof, wherein ring S represents a thiophene ring; R1 represents hydrogen, halogen, alkyl, etc.; R2 represents hydrogen, alkyl, acyl, etc.; G represents -CH2-, -CH(OH)-, -CO-, etc.; Q represents alkylene; T represents -N(Rb)(Rc) (wherein Rb, Rc represents each alkyl etc.; or alternatively Rb and Rc are combined together to form cyclic amino); D represents -CH2- or -S-; A and B represent each carbonyl or thiocarbonyl, or are null; and m and n represent each 0, 1 to 4, provided that m+n represents an integer of 4 or less. This compound is useful as an antipsychotic drug having a reduced extrapyramidal side effect.
申请公布号 US5532240(A) 申请公布日期 1996.07.02
申请号 US19940272320 申请日期 1994.07.08
申请人 YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. 发明人 NAKAO, TOHRU;ONO, YUJI;BOUGAUCHI, MASAHIRO;MORIMOTO, YASUTO
分类号 C07D495/04;C07D513/04;C07D519/00;(IPC1-7):A61K31/435 主分类号 C07D495/04
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