摘要 |
A condensed thiophene compound represented by general formula: <IMAGE> (I) or a pharmaceutically acceptable salt thereof, wherein ring S represents a thiophene ring; R1 represents hydrogen, halogen, alkyl, etc.; R2 represents hydrogen, alkyl, acyl, etc.; G represents -CH2-, -CH(OH)-, -CO-, etc.; Q represents alkylene; T represents -N(Rb)(Rc) (wherein Rb, Rc represents each alkyl etc.; or alternatively Rb and Rc are combined together to form cyclic amino); D represents -CH2- or -S-; A and B represent each carbonyl or thiocarbonyl, or are null; and m and n represent each 0, 1 to 4, provided that m+n represents an integer of 4 or less. This compound is useful as an antipsychotic drug having a reduced extrapyramidal side effect.
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申请人 |
YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. |
发明人 |
NAKAO, TOHRU;ONO, YUJI;BOUGAUCHI, MASAHIRO;MORIMOTO, YASUTO |