MICROFLUIDIC PARTICLE ANALYSIS DEVICE

摘要

The present invention relates to a microfluidic particle analysis device comprising an inlet in fluid communication via a main channel defining a main flow direction with an inlet manifold providing parallel fluid communication with a bypass channel of hydrodynamic resistance R bypass , and a measuring channel of hydrodynamic resistance R measuring , the measuring channel having a cross-sectional dimension in the range of from 1 μm to 50 μm and further having a sensor system for detecting a particle, wherein a flow distribution parameter X measuring R measuring -1 (R measuring -1 + R bypass -1 ) -1 is in the range of from 10-6 to 0.25, wherein the angle of the measuring channel relative to the main flow direction is in the range of 0° to 60°, and wherein the angle of the bypass channel relative to the main flow direction is in the range of 0° to 60°, and the microfluidic particle analysis device further comprising an outlet in fluid communication with the bypass channel and the measuring channel. The present invention relates to a method of using the device microfluidic particle analysis.