发明名称 |
Tetracyclines including non-antimicrobial chemically-modified tetracyclines inhibit excessive glycosylation of different types of collagen and other proteins during diabetes |
摘要 |
A method for treating mammals suffering from excessive extracellular protein glycosylation which is associated with diabetes, scleroderma and progeria by administering to the mammal a tetracycline which effectively inhibits excessive protein glycosylation.
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申请公布号 |
US5532227(A) |
申请公布日期 |
1996.07.02 |
申请号 |
US19940361116 |
申请日期 |
1994.12.21 |
申请人 |
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK |
发明人 |
GOLUB, LORNE M.;RAMAMURTHY, NUNGAVARUM S.;MCNAMARA, THOMAS F.;RYAN, MARIA E. |
分类号 |
A61K31/65;A61P3/08;A61P3/10;A61P17/00;A61P43/00;C07C237/26;(IPC1-7):A61K31/65 |
主分类号 |
A61K31/65 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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