| 发明名称 |
New isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them |
| 摘要 |
The present invention relates to new isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them.The present invention relates particularly to compounds of formula (I):The compounds of the present invention have pro-apoptotic properties, which enable their use in diseases involving a defect in apoptosis, such as, for example, in the treatment of cancers, autoimmune and immune system diseases. |
| 申请公布号 |
MD20160018(A2) |
申请公布日期 |
2016.07.31 |
| 申请号 |
MD20160000018 |
申请日期 |
2014.07.22 |
| 申请人 |
LES LABORATOIRES SERVIER;VERNALIS (R&D) LIMITED |
发明人 |
DAVIDSON James Edward Paul;MURRAY James Brooke;CHEN I-Jen;WALMSLEY Claire;DODSWORTH Mark;MEISSNER Johannes W.G.;BROUGH Paul;FEJES Imre;TATAI Janos;NYERGES Miklos;KOTSCHY Andras;SZLAVIK Zoltan;GENESTE Olivier;LE TIRAN Arnaud;LE DIGUARHER Thierry;HENLIN Jean-Michel;STARCK Jérôme-Benoît;GUILLOUZIC Anne-Françoise;DE NANTEUIL Guillaume |
| 分类号 |
C07D401/14;A61K31/4709;A61K31/4725;A61P35/00;A61P37/00;C07D401/10;C07D405/14;C07D409/14;C07D471/04 |
主分类号 |
C07D401/14 |
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