RESOLUTION OF IBUPROFEN USING A N-ALKYL-D-GLUCAMINE
摘要
(S)-ibuprofen can be separated from a mixture of (S)-ibuprofen and (R)-ibuprofen in high yield and enantiomeric purity in a single resolution step using an N-alkyl-D-glucamine as the resolving agent.
申请公布号
WO9619431(A1)
申请公布日期
1996.06.27
申请号
WO1995EP04932
申请日期
1995.12.13
申请人
F. HOFFMANN-LA ROCHE AG;LODEWIJK, ERIC;SCHLOEMER, GEORGE, C.;WITHERS, GREGORY, P.
发明人
LODEWIJK, ERIC;SCHLOEMER, GEORGE, C.;WITHERS, GREGORY, P.
