SOLID COMPOSITION WITH IMPROVED SOLUBILITY AND ABSORBABILITY

摘要

A solid composition with improved solubility and absorbability which comprises an extremely hardly water soluble drug having a solubility of 10 mu g/ml or below and being in the form of an amorphous substance, a polymer base and a nonionic surfactant and, when dispersed in water, forms fine particles having a particule size of 1 mu m or below and containing the extremely hardly water soluble drug sustaining the amorphous form. In the solid composition, the extremely hardly water soluble drug exudes from the fine particles, thus enabling improved absorption of the drug via the digestive tracts.