| 发明名称 |
NON-LITHOTRIPSIC KIDNEY-STONE THERAPY |
| 摘要 |
One aspect of the present invention relates to a method of using peristalsis to force a polymer plug through a mammalian lumen, thereby removing any calculi and/or calculi fragments present in the lumen. In one embodiment, the method is used as an alternative to conventional lithotripsy. In another embodiment, the method is used in conjunction with lithotripsy, thereby removing the small calculi fragments that result from such procedures. |
| 申请公布号 |
US2016249941(A1) |
申请公布日期 |
2016.09.01 |
| 申请号 |
US201514869335 |
申请日期 |
2015.09.29 |
| 申请人 |
Genzyme Corporation ;The General Hospital Corporation |
发明人 |
McDougal W. Scott;Sacco Dianne E.;Schwarz Alexander;Vogel Jean-Marie |
| 分类号 |
A61B17/22;A61K49/00;A61B17/3205 |
主分类号 |
A61B17/22 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating lithiasis, comprising the steps of:
injecting into a lumen of a mammal at a first distance upstream from a calculi a first composition comprising between 12 and 25 weight percent of an inverse thermosensitive polymer, wherein said first composition does not initially contact said calculi; thereby forming a polymer plug; and removing the calculi from the lumen by movement of the polymer plug by peristalsis to traverse said lumen, thereby forcing said calculi from said lumen. |
| 地址 |
Cambridge MA US |
