Cell degeneration suppressing and organ toxicity reducing agent

摘要

This invention provides an agent for use in the suppression of cell degeneration and reduction of organ toxicity, which comprises a sulfated glycolipid or fucosylated glycolipid of biological origin, a synthetic sulfated saccharide, or a mixture composition thereof as an inhibitor for a neutrophil surface-adhering molecule selectin. The agent of the present invention is useful as a preventive and therapeutic agent of cell degeneration and organ disorders caused by poisoning accidents and viral infection and can reduce side effects of drugs for use in the treatment of causative diseases, so that such drugs can be administered safely to patients who are apt to receive side effects due to reduced functions in the liver, kidney and the like organs, cerebral tissues and cells or who have a narrow range of the application dose of medicines like the case of pregnant women, babies, the aged and the like.