Solubilisation aids for hydrophilic macromolecules

摘要

The invention provides a process for the preparation of a single phase hyudrophobic preparation comprising a hydrophilic species in a hydrophobic solvent wherein a compound which is: (a) a low molecular weight compound having at least some degree of polarity; and/or (b) a lipid-soluble organic acid; and/or (c) an amphiphile; and (d) glycerol or other polyhydric alcohols; is added during the process to aid solubilisation.