发明名称 Apparatus and method of delivery of gas-supersaturated liquids
摘要 An apparatus 10 for delivery of a gas, such as oxygen, solution into an environment (such as a coronary artery). The apparatus includes a high pressure tubular housing 12 defining a lumen 14 therewithin. A plurality of axially disposed concentric tubes 16 are supported within the lumen 14. Each defines an annular space 18 between adjacent tubes. One or more supports 20 extend radially inwardly from the tubular housing 12. The supports are connected to the concentric tubes 16 to prevent radially or axially migration thereof during high pressure infusion of the oxygen supersaturated physiologic solution. The method includes the steps of compressing a carrier to form a compressed carrier for transporting the gas to eliminate gas nuclei before exposure of the carrier to the gas; exposing the compressed carrier to the gas under pressure to form a gas-saturated compressed carrier; transporting the gas-saturated compressed carrier to the delivery system; and infusing the gas supersaturated compressed carrier from the delivery system at an exit port to the environment without associated bubble formation and cavitation proximate the exit port so that the gas is transported to the site within the environment in solution with the carrier in a supersaturated state, the gas being liberated therefrom remote from the exit port upon arrival at the site within the environment.
申请公布号 AU4418196(A) 申请公布日期 1996.06.26
申请号 AU19960044181 申请日期 1995.12.06
申请人 WAYNE STATE UNIVERSITY 发明人 JAMES RICHARD SPEARS
分类号 A23L2/54;A61K9/50;A61M1/16;A61M1/32;A61M25/00;B01F3/04;B01F3/08;B01J13/04;C01B5/00;C01B13/00;C01B13/02;C12M1/04;D21C9/147 主分类号 A23L2/54
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