Pharmaceutical use of dihydropyridine derivative

摘要

PCT No. PCT/JP94/00460 Sec. 371 Date Feb. 24, 1995 Sec. 102(e) Date Feb. 24, 1995 PCT Filed Mar. 22, 1994 PCT Pub. No. WO94/23721 PCT Pub. Date Oct. 27, 1994.A novel pharmaceutical use of a dihydropyridine derivative of the formula (I) (I) wherein R1, R2 and R3 are the same or different and each is an alkyl or the like; R4 is a hydrogen atom or the like; R5 is nitro, a halogenated alkyl, cyano or the like; X is a vinylene or an azomethine; A is an alkylene; and B is -N(R6) (R7) or a group of the formula wherein R6 and R7 are the same or different and each is an alkyl, an aralkyl, an aryl or the like; R8 and Ar are aryl or the like; and n is 0, 1 or 2, or an acid addition salt thereof for promoting PGI2 production, and for the treatment and prevention of hyperlipemia, arteriosclerosis and cerebral diseases.