发明名称 |
Compounds and use thereof |
摘要 |
There is disclosed a compound shown by a formula of <IMAGE> wherein R1 is a hydrogen atom alkyl group having 1-4 carbon atoms or acyl group having 1-4 carbon atoms: R2 and R3 are a hydrogen atom, alkyl group having 1-4 carbon atoms, phenyl radical, halogen atom, cyano radical, acyl group having 1-4 carbon atoms, nitro radical, alkoxy group having 1 or 2 carbon atoms, or substituted or non-substituted amino group, respectively; n is an integer of 1-3; and dotted line means a possible ring, and a salt thereof. The compound and salt bind with muscarinic receptor in brain to develop a powerful actuation thereof and thus those can be used as an effective ingredient for preventing and curing senile dementias, and more particularly Alzheimer's disease.
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申请公布号 |
US5530138(A) |
申请公布日期 |
1996.06.25 |
申请号 |
US19940312638 |
申请日期 |
1994.09.27 |
申请人 |
SANWA KAGAKU KENKYUSHO CO., LTD. |
发明人 |
BABA, YUTAKA;SUZUKI, TOMOO;SUZUKI, TSUNEMASA;HIROOKA, KIYOTAKA;KURONO, MASAYASU;SAWAI, KIICHI |
分类号 |
A61K31/00;A61K31/40;A61K31/407;A61P25/00;A61P25/02;A61P25/18;A61P25/28;C07D487/04;(IPC1-7):A61K31/40;C07D451/02 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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