发明名称 Compounds and use thereof
摘要 There is disclosed a compound shown by a formula of <IMAGE> wherein R1 is a hydrogen atom alkyl group having 1-4 carbon atoms or acyl group having 1-4 carbon atoms: R2 and R3 are a hydrogen atom, alkyl group having 1-4 carbon atoms, phenyl radical, halogen atom, cyano radical, acyl group having 1-4 carbon atoms, nitro radical, alkoxy group having 1 or 2 carbon atoms, or substituted or non-substituted amino group, respectively; n is an integer of 1-3; and dotted line means a possible ring, and a salt thereof. The compound and salt bind with muscarinic receptor in brain to develop a powerful actuation thereof and thus those can be used as an effective ingredient for preventing and curing senile dementias, and more particularly Alzheimer's disease.
申请公布号 US5530138(A) 申请公布日期 1996.06.25
申请号 US19940312638 申请日期 1994.09.27
申请人 SANWA KAGAKU KENKYUSHO CO., LTD. 发明人 BABA, YUTAKA;SUZUKI, TOMOO;SUZUKI, TSUNEMASA;HIROOKA, KIYOTAKA;KURONO, MASAYASU;SAWAI, KIICHI
分类号 A61K31/00;A61K31/40;A61K31/407;A61P25/00;A61P25/02;A61P25/18;A61P25/28;C07D487/04;(IPC1-7):A61K31/40;C07D451/02 主分类号 A61K31/00
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