Use of small peptides in the treatment of psoriasis

摘要

The treatment of human patients suffering from Acquired Immune Deficiency Syndrome (AIDS) with therapeutic amounts of certain small peptides which specifically utilizes peptide T (Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr), vasoactive intestinal polypeptide (VIP), or a core pentapeptide selected from a peptide of the following formula: Thr-X-Y-Tyr-Thr where X and Y=any amino acid gamma =preferably Asp Thr1 may be repalced by D-Ala A preferred regimen for utilization of peptide T, a preferred peptide treating agent, is 1 mg twice daily for one week followed by 2 mg twice daily for three weeks, constituting an initial dosage regimen which may be repeated. This regimen has resulted in substantial increase in total white cell count assay, thus combatting the deleterious effect of the AIDS virus.