THIAZOLIDINONE COMPOUNDS OR ANGINA PECTORIS REMEDY OR PREVENTIVE CONTAINING THE SAME AS ACTIVE INGREDIENT

摘要

Constitution: a thiazolidinone compound represented by general formula (I) or a pharmacoligically acceptable salt thereof, wherein W represents sulfur or oxygen and X represents -N(R<1>)-, or alternatively X represents sulfur or oxygen and W represents -N(R<1>)-, and R<1> represents hydrogen, alkyl or substituted alkyl; R<2> and R<3> are the same or different from each other, and each represents hydrogen, alkyl, substituted alkyl, aryl, or 5- or 6- membered heteroaryl; R<4> represents hydrogen, alkyl or substituted C1-C4 alkyl; R<5> represents substituted cycloalkyl which may contain nitrogen, provided the substituents include -B-ONO2 (wherein B represents a single bond or alkylene) as the indispensable member and alkyl groups as optional members; and A represents a single bond or alkylene. Effect: the compound has an excellent anti-anginal effect and thus is useful as an angina pectoris remedy or preventive.