| 摘要 |
<p>Disclosed are compounds of formula (I), wherein R?1, R3 and R8¿ are independently alkyl, aryl or aralkyl, and R2 is selected from the group consisting of S and O, R6 is selected from the group consisting of S and O, provided that R?2 and R6¿ are not both O. The compounds are effective PDE IV inhibitors and possess improved PDE IV inhibition and improved selectivity with regard to PDE III inhibition. Methods of treatment using the compounds are also disclosed.</p> |
