发明名称 HUMAN CANCER INHIBITORY PENTAPEPTIDE HETEROCYCLIC AND HALOPHENYL AMIDES
摘要 <p>The synthesis and elucidation of nineteen heterocyclic or halophenyl amide derivatives of dolastatin (10) are disclosed. These compounds and the methods of producing those compounds offer demonstrated significant in vitro activity against several human cancer cell lines. These compounds and the methods of producing those compounds offer a commercially viable alternative to natural and synthetic dolastatin (10).</p>
申请公布号 WO1996018408(A1) 申请公布日期 1996.06.20
申请号 US1995016145 申请日期 1995.12.08
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