发明名称 NOVEL RECEPTOR
摘要 A receptor in substantially pure form obtainable from rat forebrain tissue which is characterised in that: a) compound A binds to it with a Kd of 40nM for rat forebrain tissue, b) compound A binds to it with a Bmax of 220 pmol/g protein for rat forebrain tissue, c) compound B binds to it with a Kd of 2nM for rat forebrain tissue, d) compound B binds to it with a Bmax of 220pmol/g protein for rat forebrain tissue; and homologous receptors from other sources sharing at least 85 % homology with the rat forebrain tissue.
申请公布号 WO9618650(A1) 申请公布日期 1996.06.20
申请号 WO1995EP04998 申请日期 1995.12.11
申请人 SMITHKLINE BEECHAM P.L.C.;HERDON, HUGH, JONATHAN;JERMAN, JEFFREY, CLIFFORD;CHAN, WAI, NGOR 发明人 HERDON, HUGH, JONATHAN;JERMAN, JEFFREY, CLIFFORD;CHAN, WAI, NGOR
分类号 G01N33/53;A61K38/00;A61K39/395;A61P9/10;A61P25/00;A61P25/28;A61P25/30;A61P43/00;C07B59/00;C07D311/68;C07D405/12;C07K14/705;C07K16/28;C12P21/08;C12Q1/02;G01N33/577;(IPC1-7):C07K14/705;A61K38/17;G01N33/60 主分类号 G01N33/53
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