发明名称 Thionophosphate derivatives, process for their preparation and pharmaceutical compositions containing them
摘要 The invention relates to a compound of formula (I) in which X1 and X2 each independently represents an oxygen or nitrogen atom; p, m and n are each independently an integer of at least 2; R, R1 and R2 each independently represents a hydrogen atom; a halogen atom; an optionally substituted straight-chained or branched alkyl, alkenyl or alkynyl radical; a group R3O in which R3 is hydrogen atom, an optionally substituted straight-chained or branched alkyl, alkenyl or alkynyl radical; optionally substituted acyl or optionally substituted aryl or heteroaryl; a group R4O(O)C in which R4 is a hydrogen atom or an optionally substituted straight-chained or branched alkyl, alkenyl or alkynyl radical; a group -SR5 in which R5 is a hydrogen atom or an optionally substituted straight-chained or branched alkyl, alkenyl or alkynyl radical; a group -NR6R7 in which R6 and R7 each independently represents a hydrogen atom, an optionally substituted straight-chained or branched alkyl, alkenyl or alkynyl radical; optionally substituted acyl; or an optionally substituted phosphate ester group. The invention also relates to processes for the preparation of compounds of the formula and to pharmaceutical compositions containing the same.
申请公布号 AU4408196(A) 申请公布日期 1996.06.19
申请号 AU19960044081 申请日期 1995.11.13
申请人 YISSUM RESEARCH DEVELOPMENT COMPANY 发明人 OREN TIROSH;JOSHUA KATZHENDLER;ISAAC GINSBURG;YEHEZKEL BARENHOLZ;RON KOHEN
分类号 A61K8/55;A61Q17/00;C07F9/24 主分类号 A61K8/55
代理机构 代理人
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