发明名称 |
Muramyldipeptide derivatives and influenza vaccine containing them |
摘要 |
<p>Novel muramyldipeptide derivatives such as [6-0-(2-tetradecylhexadecanoyl)-N-acetylmuramoyl]-L-alanyl-D-glutamide and [6-0-(2-tetradecylhexadecanoyl)-N-acetylmuramoyl]-L-alanyl-N -methyl-D-glutamamide are provided. The muramyldipeptide derivatives are excellent compound as an adjuvant or a constituting component of virosome vaccine. An influenza vaccine comprises a complex of the muramyldipeptide derivative and an influenza virus antigen. The influenza vaccine has excellent antibody-producing capacity and safety. <IMAGE></p> |
申请公布号 |
IL99851(A) |
申请公布日期 |
1996.06.18 |
申请号 |
IL19910099851 |
申请日期 |
1991.10.25 |
申请人 |
DAIICHI PHARMACEUTICAL CO., LTD. |
发明人 |
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分类号 |
A61K38/00;A61K38/14;A61K39/00;A61K39/145;C07K9/00;(IPC1-7):C07K9/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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