Carboxymethylidenecycloheptimidazole derivatives, method of manufacturing the same and therapeutic agents containing these compounds

摘要

New therapeutic agent of carboxymethylidenecycloheptimidazole derivatives and method for the manufacture thereof are disclosed, which are represented by the following formula or its alkali addition salts <IMAGE> (1) (wherein R1 represents a lower alkyl; R2 represents H or isopropyl group; R3 represent H, a lower alkyl or -C(CH3)H-OCOOR4 (R4 is a lower alkyl or cyclohexyl) and =CHCOOR3 is substituted group at 4 or 8 position; A represents <IMAGE> These compounds are useful as anti-hypertensive, anti-congestive heart failure agents and intraocular pressure lowering agents.