Economical manufacturing process for 1,2,3-triazoles

摘要

A high quality 1,2,3-triazole is obtained in a one pot two step reaction between appropriately substituted hydrazide derivatives, dihaloethanediol and NH3 in methanol. Synthesis of various N1-alkyl, N1-aryl, and N1-heterocyclic-1,2,3-triazoles is also accomplished following the same general procedure.