| 发明名称 |
Total synthesis of taxol |
| 摘要 |
The present invention provides two basic routes for the total synthesis of taxol having the structure: <IMAGE> The present invention also provides the intermediates produced in the above processes, processes for synthesizing these intermediates as well as analogs to taxol. Both the intermediates and analogs to taxol may prove to be valuable anticancer agents.
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| 申请公布号 |
US5527924(A) |
申请公布日期 |
1996.06.18 |
| 申请号 |
US19940350251 |
申请日期 |
1994.12.05 |
| 申请人 |
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH |
发明人 |
DANISHEFSKY, SAMUEL J.;BORNMANN, WILLIAM G.;QUENEAU, YVES;MAGEE, THOMAS V.;KROL, WALTER J. |
| 分类号 |
A61K31/335;C07C13/28;C07C45/29;C07C45/59;C07C49/603;C07C49/613;C07C49/687;C07C49/713;C07C49/723;C07C49/737;C07C49/747;C07C49/753;C07C49/757;C07C255/31;C07C255/45;C07C255/46;C07D305/14;C07D317/72;C07D339/08;C07D493/04;C07F7/18;(IPC1-7):C07D339/08;C07D317/12 |
主分类号 |
A61K31/335 |
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