发明名称 |
Antibiotics having immunosuppressive activity, delaminomycins and processes for the production of the same |
摘要 |
PCT No. PCT/JP93/00845 Sec. 371 Date Jan. 20, 1995 Sec. 102(e) Date Jan. 20, 1995 PCT Filed Jun. 22, 1993 PCT Pub. No. WO94/00430 PCT Pub. Date Jun. 1, 1994.As new antibiotics are obtained delaminomycins A, B and C having a formula (I) or (I') shown below, or salts thereof. Delaminomycins preferentially inhibit T cells and are useful as immunosuppressants, antineoplastic agents and antibacterial agents. <IMAGE> (I) <IMAGE> (I') wherein X is a hydroxyl group for delaminomycin A, a methoxy group for delaminomycin B and a hydrogen atom for delaminomycin C.
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申请公布号 |
US5527820(A) |
申请公布日期 |
1996.06.18 |
申请号 |
US19950356267 |
申请日期 |
1995.01.20 |
申请人 |
ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI |
发明人 |
ISHIZUKA, MASAAKI;UENO, MITSUHIRO;IINUMA, HIRONOBU;NAGANAWA, HIROSHI;HAMADA, MASA;MAEDA, KENJI;TAKEUCHI, TOMIO |
分类号 |
C07D207/36;C07D207/38;C07D209/96;C12P17/10;(IPC1-7):A61K31/40 |
主分类号 |
C07D207/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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