发明名称
摘要 This invention relates to novel (acyloxyalkoxy) carbonyl derivatives as a bioreversible prodrug moieties for primary and secondary amine functions in drugs having a primary or secondary amine function thereon. Hydrolytic enzymes are used to trigger the regeneration of the parent amine drug of the carbamate prodrug moiety. The case also contains pharmaceutical composition, method of treatment and process claims.
申请公布号 JP2505728(B2) 申请公布日期 1996.06.12
申请号 JP19840127732 申请日期 1984.06.22
申请人 MERCK & CO INC 发明人 JOZE AREKISANDAA
分类号 A61K31/27;A61K31/425;A61K31/433;A61K31/495;A61K31/535;A61P43/00;C07C67/00;C07C239/00;C07C271/22;C07D209/08;C07D215/56;C07D285/10;C07D417/04;C07D471/04;C07D521/00;(IPC1-7):C07C271/22 主分类号 A61K31/27
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