METHOD FOR ANTIGENIC SPECIFIC IMMUNOSUPPRESSION BY T-CELL ALPHA CHAIN

摘要

Methods for modulating immune responses in an antigen-specific fashion are disclosed. The methods utilize soluble TCR alpha chains which are capable of binding to the antigen, and which, in the presence of an accessory component, suppress the immune response in an antigen-specific manner. The use of TCR alpha chains which demonstrate such activity in therapeutic protocols for treating hyperimmune and immunodeficient conditions is described.