发明名称 |
Isolated components of dense microspheres derived from mammalian brain tissue and antibodies thereto |
摘要 |
DMS present in the brain of individuals susceptible to cerebral amyloidosis disintegrate into DMS components to form cerebral amyloid plaques and other DMS components that are removed from the brain via circulating bodily fluids. Detecting the presence of these removed DMS components in circulating bodily fluids provides a diagnostic mechanism to determine the onset of cerebral amyloid plaque formation. Antibodies also can be raised against isolated DMS components and subsequently utilized in a diagnostic method capable of detecting the onset of cerebral amyloid plaque formation.
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申请公布号 |
US5525339(A) |
申请公布日期 |
1996.06.11 |
申请号 |
US19930168250 |
申请日期 |
1993.12.17 |
申请人 |
DMS PHARMACEUTICAL INC. |
发明人 |
AVERBACK, PAUL |
分类号 |
G01N33/53;A61K31/35;A61K31/40;A61K31/42;A61K31/505;A61K31/55;A61K31/63;A61K31/655;A61K31/70;C07H17/08;C07H19/06;C07K14/47;C07K16/18;C12P21/00;G01N33/50;G01N33/68;(IPC1-7):A61K39/00 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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