| 摘要 |
PURPOSE: To obtain an antimicrobial preparation exhibiting excellent antimicrobial activity against the aggregate and lump of microorganisms, such as a biofilm or plaque, which can substantially not be controlled with an antimicrobial agent a lone. CONSTITUTION: The antimicrobial preparation contains 0.001-10wt.% of arginine or its derivative and 0.001-10wt.% of a compound exhibiting antimicrobial activity. The further addition of 0.005-5wt.% of at least a surfactant selected from a nonionic surfactant and an amphoteric surfactant to the antimicrobial preparation gives the more excellent antimicrobial effect. The compound exhibiting the antimicrobial activity includes cationic antimicrobial agents (e.g. cetylpyridinium chloride), fluorides, natural antimicrobial agents (e.g. thymol, oil-soluble glycyrrhiza extract, a polyphenol), trichlosan, and isopropylmethylphenol. The nonionic surfactant is preferably a polyethylene oxide-polypropylene oxide block copolymer, and the amphoteric surfactant is preferably a palm oil fatty acid amide propylbetaine. |
