Phenacylpyridiniothiocephalosporins

摘要

An antibacteriai 3-optionally protected-vic-dihydroxyaroyl-lower alkyl-pyridiniothiomethyl cephalosporin derivative represented by the following formula (I): (wherein, R<1> is an amino group or acylamino; R2 is hydrogen or methoxy; R3 is hydrogen or a mono- or divalent substituent; R<4> is optionally protected vic-dihydroxyaryl; R<5> is straight or branched lower alkylene; R<6> is hydrogen, a carboxy-protecting group or a negative charge when combined with Y; X is oxygen, sulfur, or sulfinyl; and Y is an anion or a negative charge when combined with R<6>; and the dotted line shows the presence or absence of a bond), a disinfecting and treating method of bacterial infection using it, and synthetic methods thereof are provided.