发明名称 |
FUSED HETEROAROMATIC CYCLOPENTENE DERIVATIVE HAVING ENDOTHELIN-ANTAGONIST ACTIVITY |
摘要 |
<p>A cyclopentene derivative represented by general formula (I) and a pharmaceutically acceptable salt thereof: wherein Ar<1> and Ar<2> represent each independently phenyl, thienyl, pyridyl, indolyl, benzofuranyl or dihydrobenzofuranyl; A represents a group that is combined with the adjacent carbon-carbon double bond to form a 5-or 6-membered heteroaromatic ring containing one to four heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur; and Y represents -CO-R<4>, SO3H, PO3H2, tetrazol-5-yl, 2-oxo-3H-1,2,3,5-oxathiadiazol-4-yl or 5-oxo-4H-1,2,4-oxadiazol-3-yl. <CHEM></p> |
申请公布号 |
EP0714897(A1) |
申请公布日期 |
1996.06.05 |
申请号 |
EP19940922382 |
申请日期 |
1994.08.16 |
申请人 |
BANYU PHARMACEUTICAL CO., LTD. |
发明人 |
ISHIKAWA, KIYOFUMI;NAGASE, TOSHIO;MASE, TOSHIAKI;HAYAMA, TAKASHI;IHARA, MASAKI;NISHIKIBE, MASARU;YANO, MITSUO |
分类号 |
A61K31/00;A61K31/44;C07D221/04;C07D401/04;C07D405/04;C07D405/14;C07D409/14;C07D413/14;C07D417/14;C07D419/04;(IPC1-7):C07D405/04 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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