发明名称 |
Detection of nucleic acids in cells by strand displacement amplification |
摘要 |
Strand Displacement Amplification for amplification of nucleic acid target sequences in situ in cells in suspension, on slides or in tissues. Excellent specimen morphology is preserved, and either DNA targets, or RNA targets, or both may be selectively amplified. In situ amplification by SDA is compatible with immunochemical techniques, so that both amplification of target sequences and immunological staining can be performed on the same specimen.
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申请公布号 |
US5523204(A) |
申请公布日期 |
1996.06.04 |
申请号 |
US19930165719 |
申请日期 |
1993.12.10 |
申请人 |
BECTON DICKINSON AND COMPANY;UNIVERSITY OF MASSACHUSETTS |
发明人 |
SINGER, ROBERT H.;MATHYS, JEAN MARIE;LOHMAN, KENTON L. |
分类号 |
C12N15/09;C12N15/00;C12Q1/68;C12Q1/70;C12R1/92;(IPC1-7):C12N15/34 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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