发明名称 Tripyridyl macrocyclic compounds
摘要 Tripyridyl macrocyclic compounds that are employed in the production of a complexing agent for use in targeting radioactive immunoreagents with the following formula are disclosed: <IMAGE> wherein R1 represents hydrogen, alkyl, alkoxy, alkylthio, alkylamino, alkylformamido, aryl, aryloxy, heterocyclyl or a protein reactive group; the two R2 groups, taken together, represent a bridging group serving to complete a macrocyclic ring, the bridging group containing at least one heteroatom and at least one alkylene group which form part of the resulting macrocyclic ring; R3 represents hydrogen, alkyl, alkoxy, alkylthio, alkylamino, alkylformamido, aryl, aryloxy, heterocyclyl, or a protein reactive group; R5 represents alkyl or alkoxy; and R6 represents a protein reactive group.
申请公布号 US5523402(A) 申请公布日期 1996.06.04
申请号 US19940287381 申请日期 1994.08.08
申请人 STERLING WINTHROP INC. 发明人 TONER, JOHN L.;HILBORN, DAVID A.;MURRAY, BRUCE J.;HOSSAIN, TIMOTHY Z.
分类号 A61K47/48;A61K49/00;A61K51/00;A61K51/10;C07D213/38;C07D213/53;C07D213/61;C07D213/74;C07D213/77;C07D401/14;C07D403/10;C07D471/04;C07D471/14;C07D471/18;C07D487/22;G01N33/534;(IPC1-7):C07D259/00 主分类号 A61K47/48
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