发明名称 |
Human dna ligase iii |
摘要 |
A human DNA Ligase III polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide via gene therapy for the treatment of disorders associated with a defect in DNA Ligase III. Antagonists against such polypeptides and their use as a therapeutic to destroy unwanted cells are also disclosed. Diagnostic assays to detect mutant DNA Ligase III genes are also disclosed. |
申请公布号 |
AU1174795(A) |
申请公布日期 |
1996.05.31 |
申请号 |
AU19950011747 |
申请日期 |
1994.11.08 |
申请人 |
HUMAN GENOME SCIENCES, INC. |
发明人 |
YING-FEI WEI;WILLIAM A. HASELTINE |
分类号 |
G01N33/50;A61K35/76;A61K38/00;A61K48/00;A61P7/06;A61P37/00;A61P43/00;C07K16/40;C12N1/21;C12N5/00;C12N5/10;C12N9/00;C12N9/88;C12N9/99;C12N15/09;C12R1/19;C12R1/91;G01N33/53 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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