摘要 |
A GL-7ACA acylase having the following characteristics: (a) has ability to catalyze the enzymatic conversion of glutaryl 7-ACA, adipyl 7-ACA, and succinyl 7-ACA, into 7-aminocephalosporanic acid, (b) has a molecular weight of 70,000 dalton (SDS-PAGE) and (c) has N-terminal amino acid sequence thereof : Gln-Ser-Glu-Gln-Glu-Lys-Ala-Glu-Glu-. A process for producing GL-7ACA acylase is also provided. |
申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD. |
发明人 |
ARAMORI, ICHIRO;FUKAGAWA, MASAO;ONO, HIROKI;ISHITANI, YOSUKE;TSUMURA, MANA;IWAMI, MORITA;KOJO, HITOSHI |