| 发明名称 |
MATRIX METALLOPROTEASE INHIBITORS |
| 摘要 |
Compounds of formula (I) and their pharmaceutically acceptable salts inhibit matrix metalloproteases, such as stromelysin, gelatinase, matrilysin and collagenase, and are useful in the treatment of mammals having disease-states alleviated by the inhibition of such matrix metalloproteases.
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| 申请公布号 |
CA2205665(A1) |
申请公布日期 |
1996.05.30 |
| 申请号 |
CA19952205665 |
申请日期 |
1995.11.21 |
| 申请人 |
SYNTEX (U.S.A.) INC.;AGOURON PHARMACEUTICALS, INC. |
发明人 |
CASTELHANO, ARLINDO L.;BENDER, STEVEN L.;YUAN, ZHENGYU;DEAL, JUDITH G.;LIAK, J. TENG;HORNE, STEPHEN E. |
| 分类号 |
A61K31/16;A61K31/195;A61K31/215;A61K31/275;A61K31/395;A61K31/66;C07C237/22;C07C255/60;C07C259/06;C07C279/14;C07C311/46;C07C317/40;C07C323/59;C07C327/34;C07D205/08;C07D209/20;C07D213/56;C07D213/75;C07D263/26;C07D295/13;C07D413/02;C07F9/30;C07F9/60;(IPC1-7):C07C237/22 |
主分类号 |
A61K31/16 |
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