| 摘要 |
The present invention provides novel compounds of the formulae (I): AG-(CH2)n-CO2R<1> and (II) or pharmacologically acceptable salts thereof, wherein AG is: a) N-aminoguanidine, b) N,N'-diaminoguanidine, or c) N,N',N"-triaminoguanidine; and n, R<1> and R<2> have the meanings given in the description as well as a new use for the compounds of formula (III) wherein R<3> has the meanings given in the description for the treatment of non-insulin dependent diabetes mellitus (NIDDM).
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| 申请人 |
THE UPJOHN COMPANY;LARSEN, SCOTT, D.;VAILLANCOURT, VALERIE, A.;MAY, PAUL, D.;TANIS, STEVEN, P.;TUCKER, JOHN, A.;MEGLASSON, MARTIN, D.;SCHOSTAREZ, HEINRICH, J. |
发明人 |
LARSEN, SCOTT, D.;VAILLANCOURT, VALERIE, A.;MAY, PAUL, D.;TANIS, STEVEN, P.;TUCKER, JOHN, A.;MEGLASSON, MARTIN, D.;SCHOSTAREZ, HEINRICH, J. |
