| 发明名称 |
METHODS FOR TREATMENT OF MULTIPLE SCLEROSIS USING PEPTIDE ANALOGS OF HUMAN MYELIN BASIC PROTEIN |
| 摘要 |
The present invention is directed toward peptide analogs of human myelin basic protein. The peptide analog is at least seven amino acids long and derived from residues 83 to 99 of human myelin basic protein. The analogs are altered from the native sequence at least at positions 91, 95, or 97. Additional alterations may be made at other positions. Pharmaceutical compositions containing these peptide analogs are provided. The peptide analogs are useful for treating multiple sclerosis.
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| 申请公布号 |
WO9616086(A1) |
申请公布日期 |
1996.05.30 |
| 申请号 |
WO1995US14403 |
申请日期 |
1995.11.16 |
| 申请人 |
NEUROCRINE BIOSCIENCES, INC. |
发明人 |
LING, NICHOLAS;GAUR, AMITABH;CONLON, PAUL, J.;STEINMAN, LAWRENCE |
| 分类号 |
A61K38/00;A61K38/17;A61P25/00;A61P25/02;A61P25/28;A61P37/00;A61P37/04;C07K14/47;(IPC1-7):C07K14/47 |
主分类号 |
A61K38/00 |
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