发明名称 |
RECOVERY OF AND USES OF SPECIFIC BINDING AGENTS |
摘要 |
An antibody specific for a target analyte is purified by affinity chromatography on a substrate bearing a low-affinity analogue of the target analyte. The antibody is displaced from the substrate by contact with a second analogue of intermediate affinity, which remains complexed with the antibody. This complex can be used in a conventional assay for the target analyte, which displaces the intermediate-affinity analogue. The complexed antibody is rendered more storage-stable because the second analogue protects the antibody binding region. |
申请公布号 |
WO9616332(A1) |
申请公布日期 |
1996.05.30 |
申请号 |
WO1995EP04518 |
申请日期 |
1995.11.16 |
申请人 |
UNIPATH LIMITED |
发明人 |
BADLEY, ROBERT, ANDREW;BERRY, MARK, JOHN;PORTER, PHILIP;WATTAM, TREVOR, ANTHONY, KENNETH |
分类号 |
G01N33/531;G01N33/58;G01N33/74;(IPC1-7):G01N33/531 |
主分类号 |
G01N33/531 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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