| 摘要 |
<p>A 2-[2-(indol-3-yl)ethylamino]-1-phenylethanol derivative represented by general formula (I) and a pharmaceutically acceptable acid-addition salt thereof, wherein R1 stands for halogen or trifluoromethyl; R2 stands for hydrogen, lower alkyl or fluorinated lower alkyl; and R3 stands for hydrogen, halogen, trifluoromethyl, nitro or cyano. This compound has a highly selective activity of stimulating β3 adrenaline receptors and is usable for treating or preventing diabetes, obesity, irritable bowel syndrome, acute or chronic diarrhea and so forth, and also for ameliorating syndromes accompanying peptic ulcer, acute or chronic gastritis, and so forth, such as abdominal pain, nausea, vomiting and epigastric discomfort.</p> |
