NOVEL (+)-(S)-2-(3-BENZOYLPHENYL)PROPIONIC ACID DERIVATIVES WITH ANALGESIC ACTION AND THE PROCESS FOR THE PREPARATION THEREOF

摘要

The present invention relates to novel (+)-(S)-2-(3-benzoylphenyl)propionic acid salts of formula (I), wherein B<+> is choline or the protonated form of lysine, arginine, ornithine, D-glucamine, N-methyl-D-glucamine or imidazole. The process for the preparation comprises reacting a compound of formula (II) with lysine, arginine, ornithine, choline hydroxide, D-glucamine, N-methyl-D-glucamine or imidazole; or reacting a salt of the compound of formula (II) with the suitable organic salt. Said compounds have a high analgesic and antiinflammatory activity.